Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair

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Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair

The bladder urothelium functions as a urine-blood barrier and consists of basal, intermediate, and superficial cell populations. Reconstructive procedures such as augmentation cystoplasty and focal mucosal resection involve localized surgical damage to the bladder wall whereby focal segments of the urothelium and underlying submucosa are respectively removed or replaced and regeneration ensues....

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ژورنال

عنوان ژورنال: Stem Cell Reports

سال: 2017

ISSN: 2213-6711

DOI: 10.1016/j.stemcr.2017.10.025